Topical Steroid Ladder

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Introduction

Topical corticosteroids are used to treat a variety of inflammatory skin conditions, including eczema, psoriasis and contact dermatitis. These are available in different formulations, including ointments, creams, gels and tapes/bandages. This article will discuss the varying potencies of topical steroids, including considerations, example preparations and cautions.

Potency

Topical steroids are available in four different potencies:

  • Mild
  • Moderate
  • Potent
  • Very potent

The required potency is dependent on the underlying inflammatory skin condition, severity and location of the inflammation, the patient’s age and response to previous treatments.

The topical steroid ladder
The topical steroid ladder The topical steroid ladder

Mild

Examples

  • Hydrocortisone 0.1%
  • Hydrocortisone 0.5%
  • Hydrocortisone 1%
  • Hydrocortisone 2.5%

Cautions

Generally safe to use on all body areas, but prolonged use should be avoided.


Moderate

Examples

  • Eumovate® (clobetasone butyrate 0.05%)
  • Betnovate-RD® (betamethasone valerate 0.025%)

Cautions

Avoid use on:

  • Eyelids

Potent

Examples

  • Betnovate® (betamethasone valerate 0.1%)
  • Diprosone® (betamethasone dipropionate 0.05%)

Cautions

Avoid use on:

  • Face
  • Eyelids
  • Genitals/groin
  • Axilla
  • Children (without dermatologist advice)

Very potent

Examples

  • Dermovate® (clobetasol propionate 0.05%)
  • Nerisone Forte® (diflucortolone valerate 0.3%)

Cautions

Avoid use on:

  • Face
  • Eyelids
  • Genitals/groin
  • Axilla
  • Children

References

  • National Eczema Society. Topical steroids factsheet. 2023. Available from: [LINK].
  • NICE CKS. Topical corticosteroids. 2024. Available from: [LINK].

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