Pharmacokinetics | Drug Excretion

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In this lecture Professor Zach Murphy will be presenting on Pharmacokinetics, specifically discussing Drug Excretion. We hope you enjoy this lecture and be sure to support us below!

Table of Contents:
0:00 Lab
0:07 Drug Excretion Introduction
0:27 Mechanism of Drug Excretion
2:19 Factors Affecting Excretion
12:37 Reabsorption
21:39 Comment, Like, SUBSCRIBE!

Pharmacology Source:
Whalen, Karen. Lippincott Illustrated Reviews: Pharmacology (Lippincott Illustrated Reviews Series). Wolters Kluwer Health.

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#ninjanerd #pharmacology #pharmacokinetics

Pharmacokinetics is the study of how drugs interact with the body, including their absorption, distribution, metabolism, and excretion. One important aspect of pharmacokinetics is drug excretion, which refers to the elimination of drugs and their metabolites from the body. The process of drug excretion primarily occurs in the kidneys, but can also occur in other organs such as the liver, lungs, and intestines.

Drug excretion is a crucial part of pharmacokinetics because it determines how long a drug remains in the body and how quickly it is eliminated. This information is important for determining the proper dosage and dosing schedule of a drug, as well as for predicting how long it will take for the drug to be cleared from the body after treatment is complete.

The main factors that influence drug excretion include the drug’s chemical properties, the rate of drug metabolism, and the function of the excretory organs. For example, drugs that are highly water-soluble are more easily excreted by the kidneys, while drugs that are highly lipid-soluble may be eliminated more slowly. Similarly, drugs that are extensively metabolized in the liver may have a longer half-life and slower excretion rates than drugs that are not metabolized as extensively.

Overall, understanding the pharmacokinetics of drug excretion is important for optimizing drug therapy and minimizing the risk of adverse effects. By understanding the factors that influence drug excretion, healthcare professionals can tailor treatment regimens to individual patients, ensuring that they receive the appropriate dose and duration of therapy for their specific condition.


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