Autonomic Pharmacology | Adrenergic Agonists

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In this lecture Professor Zach Murphy will be presenting on Adrenergic Agonists within our short series on Autonomic Pharmacology. We hope you enjoy this lecture and be sure to support us below!

Table of Contents:
0:00 Lab
0:07 Adrenergic Agonists Introduction
1:06 Adrenergic Neurons and Receptors
19:32 Adrenergic Target Organ Effects
30:34 Alpha 1 Agonists
39:38 Alpha 2 Agonists
47:48 Beta 1 Agonists
51:42 Beta 1 + 2 Agonists
56:19 Beta 2 Agonists
1:02:47 Beta 3 Agonists
1:04:07 Alpha + Beta Agonists
1:13:17 Epinephrine + Dopamine
1:22:30 Norepinephrine Graphical Representation
1:29:48 Epinephrine Graphical Representation
1:34:49 Isoproterenol Graphical Representation
1:39:11 Adrenergic Agonists Practice Problems
1:45:20 Comment, Like, SUBSCRIBE!

Supplemental Lecture: Neurology | Adrenergic Receptors —

Pharmacology Source:
Whalen, Karen. Lippincott Illustrated Reviews: Pharmacology (Lippincott Illustrated Reviews Series). Wolters Kluwer Health. Kindle Edition.

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Autonomic pharmacology is a branch of pharmacology that focuses on the study of drugs that affect the autonomic nervous system. This system is responsible for controlling involuntary functions such as heart rate, blood pressure, digestion, and respiratory rate. One of the key classes of drugs studied in autonomic pharmacology is adrenergic agonists.

Adrenergic agonists, also known as sympathomimetic drugs, are drugs that stimulate the sympathetic nervous system. This system is responsible for the “fight or flight” response, which prepares the body to respond to stress or danger. Adrenergic agonists mimic the effects of the sympathetic nervous system by activating adrenergic receptors in various organs throughout the body.

There are several types of adrenergic receptors, including alpha and beta receptors. Adrenergic agonists can be selective for one type of receptor or non-selective, meaning they activate both types of receptors. Some common examples of adrenergic agonists include epinephrine, norepinephrine, albuterol, and isoproterenol.

Adrenergic agonists have a wide range of therapeutic uses. For example, they can be used to treat asthma by relaxing the smooth muscle in the airways, or to increase blood pressure in cases of shock or hypotension. They can also be used to treat cardiac arrest or anaphylactic shock.

However, adrenergic agonists can also have adverse effects if used improperly. They can increase heart rate, blood pressure, and cause anxiety or restlessness. Overuse or misuse of these drugs can lead to serious complications such as arrhythmias or myocardial infarction.

Overall, the study of adrenergic agonists is an important aspect of autonomic pharmacology. Understanding the mechanism of action and therapeutic uses of these drugs can help healthcare professionals make informed decisions when prescribing them to patients.


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