ACE Inhibitors Pharmacology Nursing (Angiotensin Converting Enzyme Inhibitors)

ACE Inhibitors (angiotensin-converting enzyme inhibitors) pharmacology nursing review of the mechanism of action, side effects, nursing considerations etc.

ACE Inhibitors work to inhibit the RAAS (renin-angiotensin-aldosterone system). Therefore, when the angiotensin-converting enzyme is inhibited it prevents angiotensin I from converting to angiotensin II, which will help lower systematic vascular resistance and blood pressure.

Side effects of ACE inhibitors include: dry, persistent cough, hyperkalemia, hypotension, dizziness, and angioedema

Nursing considerations for ACE inhibitors include: assess blood pressure and pulse regularly, education about avoiding salt substitutes that contain potassium and avoiding a diet rich in potassium due to risk of hyperkalemia, monitoring for angioedema (swelling of the dermis and subcutaneous tissue…this is life threatening) etc.

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ACE inhibitors, also known as Angiotensin Converting Enzyme Inhibitors, are a class of drugs used in the management of hypertension, heart failure, and other cardiovascular diseases. These medications work by blocking the enzyme that converts angiotensin I to angiotensin II, which is a potent vasoconstrictor that raises blood pressure.

By inhibiting this enzyme, ACE inhibitors help to relax blood vessels, reduce blood pressure, and improve blood flow to the heart and other organs. They also help to reduce the workload on the heart, which can be beneficial in patients with heart failure.

Some common ACE inhibitors include lisinopril, enalapril, ramipril, and captopril. These medications are usually taken once daily and can be prescribed alone or in combination with other drugs.

While ACE inhibitors are generally well-tolerated, they can have some side effects, such as cough, dizziness, and low blood pressure. Patients taking ACE inhibitors should also be monitored for electrolyte imbalances and kidney function, as these medications can affect these parameters.

In nursing practice, it is important to educate patients about the proper use and potential side effects of ACE inhibitors. Nurses should also monitor patients for adverse reactions and collaborate with other healthcare providers to ensure optimal patient care.


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